Serous Epithelial Ovarian Cancer: Retrospective Analysis of 260 Cases

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Sedat Akgöl
Erhan Aktürk
İpek Yıldız Özaydın
Fatma Ölmez
Sema Karakaş
Süleyman Cemil Oğlak
Adnan Budak
Ömer Fatih Ölmez
Mehmet Şükrü Budak
Özgür Akbayır


Objective: To evaluate the outcomes of patients who were followed up and treated for serous epithelial ovarian tumor.

Materials and Methods: This retrospective study included 260 patients who were diagnosed with serous epithelial ovarian cancer, treated and followed up at Kanuni Sultan Suleyman Training and Research Hospital between January 2002 and December 2019.

Results: The mean age of the patients participated in the study was 53.4±11.6 years. Of the patients, 79.7% had advance stage and 82.4% had grade 3 tumors. The rate of complete or optimal surgery was 88.2%, while the rate of suboptimal surgery was 11.2%. While 82% of the patients received adjuvant chemotherapy, 15.7% received neoadjuvant chemotherapy. Of the patients, 80.2% had a Ca 125 value higher than 35. Despite primary cytoreductive surgery and platinum-based adjuvant chemotherapy, the recurrence rate was 66.2%, and the PFS and OS rates were 34.7±41.0 and 50.5±40.0 months, respectively.

Conclusion: The majority of serous epithelial ovarian cancers are diagnosed at an advanced stage. Despite primary situ reductive surgery and subsequent platinum-based chemotherapy, the recurrence rates are quite high.

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Akgöl S, Aktürk E, Yıldız Özaydın İpek, Ölmez F, Karakaş S, Oğlak SC, Budak A, Ölmez Ömer F, Budak M Şükrü, Akbayır Özgür. Serous Epithelial Ovarian Cancer: Retrospective Analysis of 260 Cases. Aegean J Obstet Gynecol [Internet]. 2021 Apr. 3 [cited 2021 Jun. 14];3(1):19-21. Available from:
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