Is lymphadenectomy necessary for low-risk endometrial cancer?


  • İlker Çakır Department of Gynecologic Oncology, Buca Seyfi Demirsoy Training and Research Hospital, İzmir
  • Mehmet Özeren Department of Obstetrics and Gynecology, Tepecik Education and Reseach Hospital, İzmir


endometrial cancer, lymphadenectomy, survival


Objective: The aim of this study is to investigate the effect of lymphadenectomy on disease-free survival(DFS) and overall survival(OS) in low-risk endometrial cancer cases.

Material and Methods: Patients who were operated for endometrial carcinoma with endometrioid type, The International Federation of Gynecology and Obstetrics (FIGO) stage 1A, grade 1 or 2 histology between 1994 and 2013 were included in this study. The patients were divided into two groups as those who underwent intraoperative lymphadenectomy(LA +, n=197) and those who did not(LA -, n=133). Each group was evaluated in terms of survival times and recurrences.

Results: When the LA+ and LA - groups were compared in terms of survival, no significant difference was found between the two groups about DFS(p=0,955) and OS(p=0,937). The 5-year DFS rate was 95.1% in the LA -  group and 94.9% in the LA+ group (P= 0.974). The 5-year OS rates in patients who did and did not undergo lymph node dissection were 96.8% and 97.0%, respectively, and no statistically significant difference was found between the groups (P= 0.551).

Conclusion: Performing lymphadenectomy in patients with FIGO stage 1A, grade 1 or 2, endometrioid adenocarcinoma has no effect on DFS and OS.

Key Words: Endometrial cancer, lymphadenectomy, survival




How to Cite

Çakır İlker, Özeren M. Is lymphadenectomy necessary for low-risk endometrial cancer?. Aegean J Obstet Gynecol [Internet]. 2022 Apr. 28 [cited 2024 Jul. 24];4(1):15-8. Available from: