The predictive effect of serum AMH and FSH levels alone or in combination on fertility outcome

Authors

  • Zercan Kalı Department of Obstetrics and Gynecology, Private Gözde Hospital, Malatya, Türkiye
  • Fatma Tanılır Çağıran Department of Obstetrics and Gynecology, Private Clinic, Diyarbakır, Türkiye

DOI:

https://doi.org/10.46328/aejog.v5i2.156

Keywords:

AMH,, FSH, Clinical pregnancy, Age, BMI

Abstract

Objective: To explore the roles of anti-mullerian hormone (AMH) and follicle stimulating hormone (FSH) in predicting clinical pregnancy.

Materials and Methods: Forty patients who were decided on IVF/ICSI due to different infertility etiologies were included in the study. The patients were divided into two groups according to their AMH and FSH values as having a good prognosis or a poor prognosis. The clinical pregnancy and miscarriage rates of 33 cycles with good prognosis and 17 cycles with poor prognosis were compared.

Results: In the good prognosis group, the FSH value was significantly lower than the poor prognosis group (5.98±1.04 mIU/mL vs. 13.6±3.07 mIU/mL, p<0.01), while the serum AMH level was significantly higher. (3.80±1.32 ng/mL vs 0.54±0.02 ng/mL, p<0.01). The rate of chemical pregnancy in the group with good prognosis was twice as high and significant compared to the group with poor prognosis (12 (36.3%) vs 5 (29.4%), p<0.02). In terms of clinical pregnancy rates, the group with good prognosis showed a higher frequency (33.3% vs. 23.5%, p<0.001), while miscarraige rates were higher in the group with poor prognosis (9.0% vs. 25%, p<0.003).

Conclusions: Evaluation of AMH and FSH together is critical in determining clinical pregnancy rates.

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Published

2023-09-18

How to Cite

1.
Kalı Z, Çağıran FT. The predictive effect of serum AMH and FSH levels alone or in combination on fertility outcome. Aegean J Obstet Gynecol [Internet]. 2023 Sep. 18 [cited 2024 Jun. 24];5(2):48-50. Available from: https://aejog.com/index.php/aejog/article/view/156