The effects of anti-mullerian hormone, antral follicle count, and follicle stimulating hormone values on pregnancy outcomes in a case with polycystic ovary syndrome
DOI:
https://doi.org/10.46328/aejog.v4i3.127Keywords:
Infertility, Pregnancy, Anti-mullerian hormone, Polycystic ovary syndrome, AFCAbstract
Objective: In this study, it was aimed to predict pregnancy by anti-mullerian hormone, follicle-stimulating hormone, and antral follicle count values of infertile patients with PCOS.
Methods: This retrospective study has been conducted on 555 patients diagnosed with PCOS (polycystic ovary syndrome) according to the Rotterdam Criteria, referred for infertility in the IVF Clinic of Istanbul Training and Research Hospital in the 2010-2019 study. Clinical pregnancy results have been analyzed together with anti-mullerian hormone, antral follicle count, and follicle-stimulating hormone levels.
Results: The age of the patients within the group of clinical pregnancy is significantly higher than the group without pregnancy (p ˂ 0.05). Follicle-stimulating hormone (iu/ml) and anti-mullerian hormone (ng/ml) values do not differ significantly (p 0.05) in the group with and without clinical pregnancy. For the group with clinical pregnancy, the antral follicle count value is found to be significantly higher (p ˂ 0.05) than the group without pregnancy.
The age of the patients in the group with clinical pregnancy was found to be significantly higher than the group without pregnancy. (p ˂ 0.05). Follicle stimulating hormone (iu/ml) and anti-müllerian hormone (ng/ml) values did not differ significantly in the group with and without clinical pregnancy (p 0.05). Antral follicle count value was found to be significantly higher in the group with clinical pregnancy than in the group with out pregnancy (p ˂ 0.05).
Although AFC was found to be significantly higher in the group with clinical pregnancy than in the non-pregnant group, it was examined diagnostically by ROC analysis, but the diagnostic capacity of this variable to distinguish between pregnant and non-pregnant women was not found to be sufficient. (AUC<0.70).
Conclusion: We found that anti-mullerian hormone and follicle-stimulating hormone are not related to clinical pregnancy outcomes in the infertile patient group diagnosed with PCOS (polycystic ovary syndrome). Plus, although the AFC value in the group with pregnancy was significantly higher than the group without pregnancy, its diagnostic capacity was not found to be sufficient.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 CELAL AKDEMİR, Fatma Ferda Verit
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
AEJOG is an open-access journal which means that through the internet; freely accessible, readable, downloaded, copied, distributed, printed, scanned, linked to full texts, indexed, transferred to the software as data and used for any legal purpose, without financial, legal and technical obstacles. The only authority on reproduction and distribution and the sole copyright role in this field; has been given to authors therefore they can have control over the integrity of their work, so that they are properly recognized and cited. This is in accordance with the BOAI definition of open access.
The content in Aegean Journal of Obstetrics and Gynecology (AEJOG) is protected by copyright. All copyrights of the submitted articles are transferred to the Aegean Journal of Obstetrics and Gynecology within the national and international regulations at the beginning of the evaluation process. Upon submission of their article, authors are requested to complete an assignment of copyright release form. Authors should acknowledge that they will not submit their manuscript to another journal, publish in any other language, or allow a third party to use the article without the written consent of the Aegean Journal of Obstetrics and Gynecology. When an article is published on AEJOG, it is read and reused for free as soon as it is published under a Creative Commons Attribution-NonCommercial 4.0 (CC BY NC 4.0) license. In case the article is rejected, all copyrights are given back to the authors.
The content of the article and all legal proceedings against the journal, if any, are the responsibility of the author. In addition, all financial and legal liability for the copyright of the presented tables, figures and other visual materials protected by law belongs to the authors. It is the responsibility of the corresponding author to report authors scientific contributions and responsibilities regarding the article. In case of any conflict of interest, it is the responsibility of the authors to indicate the conflict of interest in the Disclosure part of the article. Author names will be published as they are listed on the submitted Title page.
