The association of intravenous antispasmodics (hyoscine-N butyl bromide) injection with obstetric lacerations at vaginal delivery
Spasmolytics On Obstetric Lacerations
Keywords:Obstetric lacerations, spasmolytic, vaginal delivery, hyoscine-N-Butylbromide, active phase of labor
Aim: To study whether hyoscine-N butyl bromide injection affects the incidence of obstetric lacerations at vaginal birth.
Materials and methods: This retrospective cohort study consists of 15806 term pregnant women who undergone vaginal delivery, in Tepecik Training and Research Hospital, İzmir between January 2018 and December 2020. Patients who received intravenous injection of Hyoscine-N-butylbromide during the active period of labor were compared with those who did not in terms of the incidence of obstetric laceration.
Results: The data of a total of 9216 deliveries meeting the study criteria were analyzed. Hyoscine-N-butylbromide was used in 4014 of these deliveries(HBD), and it was not used in 5202 of these deliveries. In both primigravid and multigravid patients in the HBD group, the first stage of delivery was found to be shorter than in patients who did not receive spasmolytics(p <0.001).There was no difference between the groups in terms of the second stage of labor. Intravenous injection of Hyoscine-N-butylbromide in the active phase of labor significantly reduced 1st and 2nd degree obstetric lacerations in primigravid patients, but had no effect on 3rd and 4th degree obstetric lacerations.
Conclusion: Hyoscine-N-Butylbromide shortens the active phase of labor and reduces minor obstetric lacerations in primigravid women.
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