Comparison of serum c-type natriuretic peptide levels in different genders: A pilot study

C type natriuretic peptide and reproduction

Authors

  • Yusuf Özay
  • Ali Cenk Özay
  • Oguzhan Edebel https://orcid.org/0000-0002-3406-6927
  • Özlen Emekçi Özay Near East University, Faculty of Medicine, Department of Obstetrics and Gynecology
  • Yasemin Türkcan Çavdarlı
  • Namık Kemal Duru

DOI:

https://doi.org/10.46328/aejog.v4i2.109

Abstract

OBJECTIVE

Firstly we aimed to compare serum C-type natriuretic peptide (CNP) levels in healthy male and female participants of similar age group and secondly to reveal the relationship between serum CNP values and ovarian function markers in women and sperm parameters in men.

MATERIAL and METHODS

In this prospective study, a total of 40 patients, who were admitted to the Department of Obstetrics and Gynecology at Near East University Hospital were included. Of these, 20 were female and 20 were male participants. Serum CNP levels of the patients were analyzed for all participants. Day 3 serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH) and estradiol (E2) for female participants and semen samples after 3-5 days of sexual abstinence for male participants were evaluated.

RESULTS

Serum CNP levels were similar in both genders. There was only a moderate, but statistically insignificant negative correlation between serum CNP and FSH in female group. In the correlation analysis performed in the male group, no significant correlation was observed between serum CNP level and any semen analysis parameter.

CONCLUSION

We showed that serum CNP levels were similar between healthy women and men. There was no relationship between levels of serum CNP and reproductive hormones in the early follicular phase of menstruation in women, and semen parameters in men.

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Published

2022-09-01

How to Cite

1.
Özay Y, Özay AC, Edebel O, Emekçi Özay Özlen, Türkcan Çavdarlı Y, Duru NK. Comparison of serum c-type natriuretic peptide levels in different genders: A pilot study: C type natriuretic peptide and reproduction. Aegean J Obstet Gynecol [Internet]. 2022 Sep. 1 [cited 2022 Sep. 26];4(2):22-5. Available from: https://aejog.com/index.php/aejog/article/view/109